As we have been discussing, Cell-El Ltd is studying ASD biomarkers in the blood, urine and stool related to immune dysfunction that may be very helpful for diagnosis and treatment. There is a great deal of interest and work being done related to immune dysfunction in individuals with ASD.
- Immunological and autoimmune considerations of Autism Spectrum
- and Autism Spectrum Disorders (ASD) – Searching for the Biological Basis for Behavioral Symptoms and New Therapeutic Targets
- also Immune Endophenotypes in Children With Autism Spectrum Disorder
- T Cell Populations in Children with Autism Spectrum Disorder and Co-Morbid Gastrointestinal Symptoms
- plus more links on our Publications page.
We also are looking at the issue of familial autoimmune conditions specifically – as this too has been often identified in the literature. This means that there is often a relationship within families of one or more members who have been diagnosed with a variety of autoimmune conditions and prevalence of children with ASD (see The Role of the Immune System in Autism Spectrum Disorder and Autism-Specific Maternal Autoantibodies Produce Behavioral Abnormalities in an Endogenous Antigen-Driven Mouse Model of Autism for example).
There are many existing theories regarding immune dysfunction in ASD. Our current thinking at Cell-El Ltd is that by helping the immune system to modulate, we may also improve behavior and overall development of individuals with ASD. By testing children with ASD before and after treatment we will examine behavioral changes as well as changes in their biomarkers – and improve our understanding of how changes in the two may be related.
Please join us in making a difference in the lives of children with ASD and their families! We are recruiting both participants who are typically developing as well as those diagnosed with ASD. We are also looking for parents to help spread the word to others and thus enable this important tool to be integrated into Autism treatment as quickly as possible. And we want to hear from you about your concerns and challenges relating to ASD testing and associated therapies. To contact us and learn more – please click here.