Analyzing the effects of Stem Cell treatment in older children

At the start of 2024, Cell-El researchers chose to broaden our biomarker analysis study. The study had included 2–12 year-olds undergoing Stem Cell Therapy (SCT). In now includes an additional cohort of 13-18 year olds. The rationale for including this new population is to understand if such therapy can affect older children who in theory have less brain plasticity.  

Cell-El plans to study the participants’ proteomic biomarkers (proteomics refers to proteins expressed by the cells) pre and post treatment. The study is based on a simple blood test as well as stool and urine collection.  If you are planning to provide your child or young adult with Stem Cell Therapy, please contact Leah or fill out this form and sign up for our diagnostic study. Currently, this study is only open to participants residing in Israel. 

Cell-El has chosen to observe the changes in these biomarkers specifically after undergoing SCT as there has been preliminary evidence that stem cells can have an immune-modulating effect on the body. See:

Parents and clinicians have reported significant changes to the ASD related symptoms after SCT. Cell-El is now investigating if there is an underlying biomedical dysfunction prior to treatment as well as any treatment induced changes both biomedically and as evidenced by improved outward behaviors and clinical symptoms.  We hope that improving our understanding of the value of these biomarkers could lead to utilizing them as a guide to diagnosis and perhaps even treatment choices for ASD. 

What are biomarkers?

 A biomarker is a biological indicator that can be measured and tells us something about a normal or abnormal biological state or a response to a therapeutic intervention or drug. For example – you can do a blood test and see that your hemoglobin is low and know that you are lacking iron.  Biomarkers can be measured in the blood, urine, stool or on tests such as an MRI, CT, EEG, et cetera. They are objective measures which can be measured with precision. 

Click here to learn more about biomarkers and their potential to guide diagnostics and treatment.

Help Us Help You

Better diagnostics for ASD based on laboratory-measured objective biomarkers can possibly enable researchers and clinicians to provide more precise and personalized treatment. You too can make a difference in the lives of children with ASD and their families by joining the Cell-El study. Cell-El is recruiting for two of our study cohorts. We are recruiting mothers, and their infants aged 10-19 months who have not been diagnosed with ASD but who have a sibling diagnosed with ASD. Cell-El is also recruiting children diagnosed with ASD between the ages of 2-18 years old whose parents are planning to take them privately to a clinic offering Stem Cell treatment for ASD. 

Please contact Leah at [email protected] or fill out the form to find out about eligibility to participate in  our diagnostic study and please help spread the word about the Cell-El study. Sharing our study will enable our important biomarker diagnostic tool to be integrated into autism treatment as quickly as possible.